Identification of possible serious bacterial infection (PSBI) and timely initiation of appropriate antibiotic treatment can dramatically increase a newborn’s chance of survival.
Recent research has shown that when hospitalization is not possible, a safe, effective, and simpler antibiotic treatment can be provided in lower-level facilities.
number of neonatal deaths attributed to neonatal infections per year
estimated number of neonatal PSBI cases that required treatment in 2012
PSBI Community of Practice (CoP)
The PSBI CoP defines itself as “groups of people who share a concern or passion for something they do and learn how to do it better as they interact regularly.” These groups facilitate the collective pursuit of a shared interest through relationship building, learning and information sharing about a specific practice area or need. They also stimulate dialogue, capture and diffuse existing knowledge, support collaboration, organize members around purposeful action, generate new knowledge and help to connect people who might not ordinarily interact. Given these features, COPs are uniquely positioned to help drive the research-to-use process by supporting stakeholder engagement, knowledge management, research translation, and research dissemination.
- Managing possible serious bacterial infection in young infants when referral is not feasible.
- Safety and efficacy of alternative antibiotic regimens compared with 7-day injectable procaine benzyl penicillin and gentamicin for outpatient treatment of neonates and young infants with clinical signs of severe infection when referral is not possible: a randomized, open-label, equivalence trial.
- Simplified antibiotic regimens compared with injectable procaine benzyl penicillin plus gentamicin for treatment of neonates and young infants with clinical signs of possible serious bacterial infection when referral is not possible: a randomized, open-label, equivalence trial.
- Oral amoxicillin compared with injectable procaine benzyl penicillin plus gentamicin for treatment of neonates and young infants with fast breathing when referral is not possible: a randomized, open-label, equivalence trial
Outpatient treatment for neonates and young infants with clinically suspected severe infection