Science in Action: Saving the Lives of Africa’s Mothers, Newborns and Children presents an overview of the current status of maternal, newborn, and child health (MNCH) in sub-Saharan Africa and reports a new analysis of how many lives could be saved if science translated into action through health systems. This publication was prepared for the Fifth Annual Meeting of the African Science Academny Development Initiative (ASADI), hosted by the Ghana Academy of Arts and Sciences on 10-11 November 2009 as part of its 50th anniversary celebration. ASADI is a project funded by The Bill & Melinda Gates Foundation through the United States National Academies to strengthen African academies of sciences in advising their national governments on matters of science and technology. This report includes data for all sub-Saharan Africa but focuses specifically on the seven countries participating in ASADI.