This toolkit is designed to equip faith actors and related stakeholders—such as Ministries of Health, medical and scientific bodies, and non-profit organizations that partner with or work alongside faith actors—with the information and tools needed to raise awareness, reduce misinformation, and address barriers that prevent faith communities in particular from engaging in vaccination. It includes information on theological dimensions of vaccination, holding discussions on vaccination, messaging on social media, holding inter-faith discussion forums on vaccine promotion, organizing harmonized inter-faith vaccine campaigns, and engaging with faith-based scientific technical bodies. Ultimately, this toolkit is intended to promote innovative partnerships that drive vaccine acceptance and uptake and to inspire increased strategic discussion and investment among stakeholders in the vaccine space.